Head and neck squamous cell carcinoma (HNSCC) is the most prevalent histopathological subtype of head and neck malignancies. Owing to the lack of early specific symptoms, the majority of patients are diagnosed at intermediate or advanced stages, which is associated with an unfavorable prognosis and a substantial decline in quality of life. Radiomics, which leverages large-scale medical imaging data, enables the extraction of high-dimensional quantitative features through advanced image analysis,...

CONCLUSIONS: HDR was performed in 5% of CTO PCIs in 2025, in more complex lesions and was associated with lower technical success but similar MACE compared with patients who underwent CTO PCI without HDR.

Airway remodeling, a hallmark of asthma, involves structural and functional changes in the airways including extracellular matrix (ECM) deposition, airway smooth muscle (ASM) cell hypertrophy and hyperplasia, epithelial and fibroblasts remodeling, and mitochondrial dysfunction driven by chronic inflammation. The aryl hydrocarbon receptor (AhR), a ligand-activated transcription factor commonly known for mediating xenobiotic responses, has recently emerged as a key regulator of cellular processes...

Over the past few decades, magnetic nanoparticles (MNPs) have emerged as a focal point of research due to their versatility and diverse applications across biomedical and technological domains. The rapid advancement in nanotechnology has enabled MNPs to be utilized in drug delivery, magnetic resonance imaging (MRI), and cancer therapy. In biomedical applications, MNPs are valued for their small size, biocompatibility, and responsiveness to external magnetic fields, facilitating targeted drug...

CONCLUSION: Patients can have a high expectation of return to wildlife sports following shoulder surgery. Surgeons are most restrictive in return to wildlife sports following ARCR of massive tears.