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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

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The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

imgPatients

The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Photic Niche Explains Avian Behavioral Responses to Solar Eclipses

2 months ago
Solar eclipses rapidly alter abiotic conditions and thus represent natural experiments for understanding how animals respond to ephemeral environmental change. Using a large acoustic dataset (181 species, 873 locations) from participatory science, we quantified how birds changed their vocalizations in response to the 2023 annular and 2024 total eclipses in North America. During the total eclipse, most species vocalized less, but nocturnal and large-eyed species vocalized more. The generalized...
Neil A Gilbert

Characterization of the Crustacean Methyl Farnesoate Transcriptional Signaling Genes

2 months ago
Methyl farnesoate (MF) is a sesquiterpenoid hormone that controls a variety of physiological processes in crustaceans, including morphogenesis, development, reproduction, and molting. MF action is mediated by a transcriptional signaling cascade consisting of Methoprene-tolerant (Met), Steroid receptor coactivator (Src), Krüppel homolog 1 (Kr-h1), and Ecdysone response gene 93 (E93) transcription factors (TFs), and transcriptional co-regulators CREB-binding protein (CBP) and C-terminal-binding...
Vanessa L Bentley

Toward an Emerging Public Health Paradigm: Agriculture and Food Production for Health

2 months ago
An emerging paradigm in public health focuses on enhancing nutrition in existing food staples to reduce chronic disease at the population scale, rather than relying on individuals to change their behavior. This paradigm leverages plant and animal breeding, production practices, and processing to enhance nutrition, whereby foods consumed by millions can be improved at low incremental cost. This article supports and operationalizes this paradigm, illustrating the potential to improve diets through...
Rod Wallace

Comparison of Heart Failure Hospitalizations with and Without Respiratory Syncytial Virus: A Nationwide Administrative Data Analysis

2 months ago
Background: Heart failure (HF) remains a major cause of hospitalizations in the United States (US). Respiratory syncytial virus (RSV) has been associated with HF exacerbations. We compared in-hospital outcomes and healthcare utilization among US HF hospitalizations with and without RSV. Methods: Using the Nationwide Readmissions Database (2016-2022), we propensity-matched HF hospitalizations with a secondary diagnosis of RSV (HF-RSV) 1:1 to those without RSV (HF-noRSV). Multivariable logistic...
Nikita Patil

LncRNAs at the Crossroads of Precision Nutrition and Cancer Chemoprevention

2 months ago
Cancer remains a leading cause of morbidity and mortality worldwide, and effective strategies for cancer prevention are urgently needed to complement therapeutic advances. While dietary factors are known to influence cancer risk, the molecular mechanisms that mediate inter-individual responses to nutritional exposures remain poorly defined. Emerging evidence identifies long non-coding RNAs (lncRNAs) as pivotal regulators of gene expression, chromatin organization, metabolic homeostasis, immune...
Camelia Munteanu

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