CONCLUSION: The lack of effective recruitment and retention strategies in thyroid cancer trials perpetuates the underrepresentation of marginalized populations, limiting the generalizability of findings. To address these disparities, clinical trials must adopt inclusive methodologies and transparent reporting practices, supported by policy changes and stronger enforcement of diversity mandates. These steps are essential for ensuring equitable health outcomes and advancing the quality of thyroid...

CONCLUSIONS: Outcome modifications are frequent in sinonasal trials but are rarely transparently documented. Given the central role of symptom-based, quality-of-life, and endoscopic outcomes in rhinology, clearer documentation of outcome changes is essential to support interpretability and evidence synthesis.

Hereditary thrombotic thrombocytopenic purpura (hTTP) is a rare inherited blood disorder caused by severe ADAMTS13 deficiency due to biallelic ADAMTS13 mutations, leading to life-threatening complications across the life span. Its impact on long-term psychological, cognitive, and overall well-being remains poorly understood. This study evaluated patient-reported outcomes in individuals with hTTP, comparing them to the general US population and patients with other chronic conditions, and assessed...

CONCLUSIONS: Experience of discrimination appears to adversely impact smoking cessation among adults with socio-economic disadvantage who are trying to quit smoking and warrants attention in cessation interventions.

The importance of examining human papillomavirus (HPV) vaccine-related conspiratorial thinking and its effects has become more prominent amid the global increase in anti-vaccine activism. However, little is known about how conspiratorial thinking shapes vaccine-related outcomes and how these processes vary across sociocultural contexts. Using survey data from China (N = 619) and the United States (N = 600), this study distinguishes between conspiracy orientation and conspiracy attribution in the...