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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

imgResearchers

The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

imgProviders

The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

imgPatients

The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Diminished variability of alpha and beta band-limited power as a neural signature in schizophrenia

1 month 3 weeks ago
Spectral features of the electroencephalogram (EEG) are essential for providing clinically relevant biomarkers in schizophrenia (SZ). Despite literature indicating altered short-scale neural dynamics in SZ, however, band-limited power (BLP) indices are rarely assessed in a time-resolved manner. To address this, here we evaluated static and dynamic BLP indices in a sample of 30 SZ patients and 31 healthy control (HC) individuals. Guided by recent findings on power spectral dynamics in SZ, we...
Frigyes Samuel Racz

Precisely designed keystone metabolites boost shrimp disease resistance by recruiting symbionts via the lipoxin A4-AP-1 pathway

1 month 3 weeks ago
CONCLUSIONS: Our findings demonstrate that precisely designed keystone metabolites enhance shrimp disease resistance through the recruitment of key symbionts-LXA4-AP-1 axis. The rationally designed keystone metabolites and SynCom are compelling biocontrol solutions in improving host disease resistance. Video Abstract.
Haonan Sha

Digital Mental Health: Progress but not Perfection

1 month 3 weeks ago
No abstract
Caleb W Lack

Virtual Reality and Mental Health: A Review of Current Findings and Needed Expansions

1 month 3 weeks ago
Virtual reality (VR) has generated growing enthusiasm as a tool to deliver evidence-based mental health treatments. By immersing individuals in interactive, simulated environments, VR allows for repeated exposure to feared stimuli, real-time practice, and clinician involvement. While the strongest evidence supports using VR exposure therapy for anxiety-related disorders, promising applications are emerging across a range of conditions. Despite promising findings, most studies have small samples...
J Kyle Haws

Therapy Without a Therapist: Chatbots and Artificial Intelligence in Mental Health

1 month 3 weeks ago
A number of articles have heralded the use of artificial intelligence (AI) agents to serve as a replacement for human psychotherapists. Despite the rapid advancements in the use of both rule-based and generative AI programs in the recent past, an overall review shows only small impacts on certain mental health symptoms, particularly depression, and then only in the short-term. Significant strides forward, both in terms of technology and the development of answers to ethical questions regarding...
Caleb W Lack

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