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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

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The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

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The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Microbial inoculations enhance soil aggregation and carbon stabilization via root exudate-mediated microbial association networks

1 month 1 week ago
Whether and how root exudates of Amorpha fruticosa Linn. mediate the positive effects of microbial inoculation (Bacillus thuringiensis NL-11 and Gongronella butleri NL-15) on soil aggregation remains unclear. We conducted two glasshouse experiments and a controlled laboratory incubation experiment to address this knowledge gap. Glasshouse experiments showed that microbial inoculation increased root exudation, changed soil microbial community structure, and enhanced soil aggregation and mean...
Chong Li

<em>Stenotrophomonas testudinis</em> sp. nov., isolated from the faecal material of a painted turtle living in the wild

1 month 1 week ago
Stenotrophomonas is a genus of Gram-stain-negative bacteria commonly found in the environment, while the species Stenotrophomonas maltophilia is an opportunistic pathogen with intrinsic resistance to carbapenems. A Gram-stain-negative rod-shaped bacterial strain, designated 9A^(T), was isolated from the faecal material of a wild turtle in Wisconsin. The genome of the isolate was sequenced by Illumina whole-genome sequencing. Ribosomal multilocus sequence typing showed that it belonged to the...
Thomas J Grachan

From road to rage: Why commute demands are associated with interpersonal counterproductive work behaviors (and what to do about it)

1 month 1 week ago
Previous literature on commute demands, or the presence of stressors during a commute, has largely concluded that affective processes do not account for the impact of commuting on employees' work behavior. In this article, we challenge this conclusion by showing that when the specific affective state aligned with the distinctive characteristics of commute demands is identified, it spills over into counterproductive work behaviors. Based on core affect theory (Russell, 2003), we propose that...
Jake Gale

Pharmacist antithrombotic interventions in critically ill children: A multicenter prospective study

1 month 1 week ago
CONCLUSION: The majority of antithrombotic interventions in critically ill children were in the PCICU and involved anticoagulation for thromboembolism treatment and prevention. Further research is warranted to evaluate pediatric pharmacist-driven clinical services and the impact on antithrombotic outcomes in critically ill children, particularly those with cardiac disease.
Amy L Kiskaddon

MicroRNA-873 Suppresses Viability and Invasion of Colorectal Cancer Through KRAS/MAPK Signaling and Sensitizes Tumor Spheroids to 5-Fluorouracil in a 3D Microwell Model

1 month 1 week ago
Colorectal cancer (CRC) ranks third in incidence among all malignancies and is highly lethal in advanced stages. Combination chemotherapy regimens based on 5-fluorouracil (5-FU) remain the mainstay of colorectal cancer treatment alongside surgical resection. Even though new treatment modalities are emerging, many are either ineffective against KRAS-mutant tumors or prone to therapy resistance. Therefore, there is a critical need for new targeted therapies that may overcome the KRAS-driven...
Mehrdad Bandegi

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