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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

imgProviders

The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

imgPatients

The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

RAiSE (recognizing affective state in equine) and the assessment of equine affective state: Accuracy and application

1 month 1 week ago
CONCLUSION: The online course RAiSE can be an effective tool to increase users' ability to recognize AS in horses, and to create human behavior change to improve equine welfare.
Kristina Hiney

Effects of Ankylosing Spondylitis on Total Knee Arthroplasty Outcomes and Post-operative Manipulation Under Anesthesia Rates

1 month 1 week ago
CONCLUSION: The AS patients undergoing TKA do not demonstrate an increased risk of joint-related complications or MUA compared to non-AS patients within the limits of this claims-based analysis; however, AS patients exhibited higher rates of postoperative anemia and UTIs.
Marc N Gadda

Predictors of Skeletal-Related Events and Quality-of-Life Dimensions Among Patients With High-Risk Asymptomatic Bone Metastases With or Without Early Radiation Therapy: Secondary Analysis of a Multicenter Randomized Phase II Clinical Trial

1 month 1 week ago
CONCLUSIONS: Rates of SRE were high among patients with bone metastases, and these findings underscore the importance of early RT in their prevention. Patient-reported QoL suggests preservation of self-care with early RT, and that survival beyond 6 months may be needed to observe a benefit. Further research regarding patient selection and the impact of SRE on QoL and functionality are needed, and a phase III randomized trial (NRG CC014; NCT06745024) is in progress.
Kaitlyn Lapen

Glucocorticoid Receptor and Cell Cycle Regulator (E2F2) Cooperatively Transactivate a Cis-Regulatory Module in the HSV-1 Infected Cell Protein 0 (ICP0) Promoter

1 month 1 week ago
Human alpha-herpesvirus 1 (HSV-1) acute infection culminates in life-long latency in sensory neurons in trigeminal ganglia and certain neurons in the central nervous system. Previously, E2F family members and glucocorticoid receptor (GR) were shown to stimulate HSV-1 and bovine herpesvirus 1 (BoHV-1) replication. Consequently, we hypothesized GR and E2F family members activate certain HSV-l promoters. To test this hypothesis, we determined if four HSV-1 ICP0 cis-regulatory modules (CRM) upstream...
Kaushalya Jayathilake

Perceived Barriers and Facilitators to Physical Activity Engagement Among Cancer Survivors: A Qualitative Study

1 month 1 week ago
Background: Although physical activity (PA) offers substantial physical and psychosocial benefits, engagement remains suboptimal among cancer survivors. A theory-informed understanding of survivors' perceived barriers, facilitators, and recommendations is needed to inform patient-centered PA about survivorship interventions. Objective: This study aimed to explore perceived barriers, facilitators, and recommendations for PA engagement among adult cancer survivors using the Theoretical Domains...
Gaurav Kumar

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