CONCLUSIONS: Increased operative time was found to be an independent risk factor for complications following ACL reconstruction for skeletally immature patients. Specifically, operative time was associated with surgical site infection and arthrofibrosis. Future efforts to improve operative efficiency are warranted to improve patient outcomes.

Vagus nerve stimulation (VNS) has been shown to improve chronic pain, including fibromyalgia, migraine headaches, and gastrointestinal pain, as well as inflammation in RA. Here, we investigated the efficacy of transcutaneous VNS (tVNS) in providing pain relief in a mouse model of post-traumatic osteoarthritis (PTOA). Destabilization of the medial meniscus (DMM) surgery was performed in 16-wk-old female and male mice. Beginning at 4 wk post-injury, mice were randomized to receive tVNS (10 min...

Several theories of fertility behavior assume that planning is important to women. Is this a reasonable assumption? To answer this question, the authors used the National Survey of Fertility Barriers. Among women with unsure or positive fertility intentions at wave 1, most (75 percent) agreed with the statement "It is important to plan my pregnancies." Logistic regression, adjusted for control variables, indicated that fertility intentions are a distinct construct from pregnancy planning...

CONCLUSIONS: Individual characteristics, attitudes, life course, and social cues are associated with changes in personal fertility ideals. More characteristics were associated with decreases than increases in personal fertility ideals.

Age-related loss of innervation in skeletal muscle is a key driver of sarcopenia. We investigated the role of calcium-dependent phospholipase A(2) (cPLA(2)) in denervation-atrophy. cPLA(2) mediates the release of polyunsaturated fatty acid substrates, and the oxidation of the free fatty acids generates oxylipins, which are bioactive signaling facilitators. We hypothesized that loss of cPLA(2) would protect against muscle atrophy by altering hydroperoxide and oxylipin generation, thereby...