Artificial Intelligence (AI) plays an increasingly significant role in drug research and development, particularly in drug repurposing, which involves identifying new therapeutic indications for existing pharmacological compounds. From classical algorithms-based tools e.g. DrugRep and DrugRepo, to more recent innovations (e.g. RosettaVS, RepurposeDrugs), this paper reviews the latest AI methods (e.g. AlphaFold3, mediKanren, AdaDR, TxGNN) and their design applications in drug repurposing,...

This paper establishes the simplicity of the Hodge bundle, a theorem in the branch of modern mathematics known as algebraic geometry. Notably, the essential mathematical content was autonomously generated by Aletheia, a custom AI agent powered by Gemini Deep Think.

CONCLUSIONS: Provision of higher and lower wattage e-cigarettes to adults who smoked and were not interested in quitting resulted in comparable substitution rates. Complete switching from cigarettes to higher and lower wattage e-cigarettes reduced urinary 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol.

CONCLUSION: Strengthening the explicit integration of Equity, Inclusion, and Systemic Change can guide nursing education, policy, and leadership to advance equitable care for all persons with IDD, ultimately shaping a more inclusive healthcare workforce.

Workaholism, also referred to as problematic overworking, has received increasing attention due to its adverse consequences for individuals, families, and organizations. This perspective paper argues that workaholism represents a largely neglected risk factor for unhealthy aging, as sustained exposure to excessive and compulsive work might be associated with an increased risk of cardiometabolic conditions, including hypertension and cardiovascular disease. We further highlight that, despite the...