The timing and nature of gestational stress can alter offspring immune function and hypothalamic-pituitary-adrenal (HPA) axis regulation, yet the role of maternal stress history remains poorly understood. This study evaluated the effects of prenatal stress, maternal stress history, and repeated stress exposure on immune and stress reactivity in prenatally stressed (PS) gilts across two farrowings. Eleven PS second-parity sows (197.27 ± 19.22 kg) were sampled at multiple timepoints and compared...

(1) Background: Regular school attendance is foundational to students' academic achievement, social-emotional development, and long-term career success. Yet chronic absenteeism continues to affect a substantial proportion of PreK-12 students in the United States, underscoring the urgent need for evidence-based interventions. (2) Methods: This meta-analysis synthesized findings from 13 randomized controlled trials and quasi-experimental studies published between January 2020 and March 2025 and...

Upper tract urothelial carcinoma (UTUC) presents distinct diagnostic and therapeutic challenges because of its rarity, anatomic constraints, frequent understaging at biopsy, and risk of systemic recurrence after radical nephroureterectomy. Current perioperative management is driven primarily by clinicopathologic risk factors, which may be insufficient to identify occult molecular residual disease (MRD) or to determine which patients are most likely to benefit from systemic therapy. This...

CONCLUSIONS: A subset of localized prostate cancer patients demonstrated linked insulin pathway changes that are consistent with prior studies describing a pattern of insulin dysregulation. Though the group characterized by insulin dysregulation initially showed worse survival outcomes, this difference disappeared when controlling for confounders. Though baseline differences in tumor stage seemed to most readily explain the difference in survival between clusters, mediation analysis showed that...

CONCLUSIONS: We were able to show corroborating evidence that ACC-EV system can provide safer, more stable, and more comfortable driving behavior compared to those of the ACC-ICEV system for the two distinctive scenarios. Furthermore, the results imply that a human driver using the ACC-EV system might feel less stressed and require less cognitive effort to maintain constant vigilance due to the enhanced safety, consistency, and comfort, contributing to traffic accident prevention.