BACKGROUND: Polygenic risk scores (PRSs) improve prediction of the development of type 2 diabetes over the use of clinical risk factors alone; however, they perform poorly in populations of non-European ancestry, limiting their global clinical utility. We aimed to deliver comprehensive and rigorously tested multi-ancestry PRSs for prediction in type 2 diabetes.

CONCLUSIONS: No previous studies have focused on the symptom and diagnostic experiences of farmers and ranchers with AGS. Capturing such data is essential as these workers may experience unique occupational challenges following AGS diagnosis. The diagnostic experience data support a continuing need to educate and empower AGS patients and providers, especially agricultural workers and providers serving rural communities.

Fetal bovine serum (FBS) is a valuable byproduct of cattle production, critical for vaccines, cell therapy, and other cell growth applications. Despite its value, cattle producers are not given incentives to increase FBS supply. This paper describes the FBS production process and investigates the economic and institutional barriers to increasing FBS production. The marketing channels and production process are described by interviews with industry employees. Opinions from these interviews led us...

Ringtails (Bassariscus astutus) are widely distributed in the western United States and across much of Mexico, yet due to their relatively low densities and cryptic nature, little is known about their basic ecology even where they are common. Recent public sightings suggest ringtails may have expanded their distribution north into southern Idaho, USA. Currently, ringtails remain unclassified in Idaho thus limiting resources and time available for population monitoring. We attempted to detect...

CONCLUSION: Findings highlight the need for interventions that strengthen affirming family and peer support networks to foster resilience among SGM young adults in ways that reduce mental health symptoms, tobacco use, and binge drinking.