BACKGROUND: Childhood cancer, though rare, remains the leading cause of disease-related death among children in the United States. The overall incidence has been rising for the past several decades, and the factors underlying the increasing rates are unclear. This unexplained increase underscores the critical need for high-quality, well-powered epidemiologic research to elucidate causes and the natural history of childhood cancers.

CONCLUSIONS: A plurality of participants favored having access to abortion. PR stress was common and was associated with mental health concerns.

CONCLUSIONS: PwCF and care partners face substantial financial burdens, with greater burdens among those with lower incomes. Many also report healthcare tradeoffs, which may impact long-term health outcomes.

CONCLUSION: Coping in patients with breast cancer post-surgery is multifaceted, varying by individual perception and psychosocial wellbeing. Future research is needed to guide interventions that bolster psychosocial well-being to promote healthy coping.

Obesity has emerged as a global health crisis and a potent driver of cancer incidence and mortality, yet its mechanistic impact on tumor biology remains underappreciated. Far from being a passive risk factor, obesity acts as a systems-level oncogenic stressor, reshaping hormonal signaling, immunometabolism, and epigenetic stability across the body. This review synthesizes current knowledge on the physiological, cellular, and molecular cascades linking obesity to carcinogenesis, with emphasis on...