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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

imgResearchers

The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

imgProviders

The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

imgPatients

The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Intermolecular Interactions Enhance the Light Absorption of a Methoxyphenol Constituent of Biomass Burning Emissions

3 months ago
Brown carbon (BrC) components of biomass burning organic aerosol (BBOA) absorb sunlight at visible wavelengths. However, it is not clear whether the total light absorption of this BrC is simply the sum of the contributions of the individual components or whether the components can bind noncovalently to give additional absorption through charge transfer. Here, intermolecular interactions between guaiacol and quinones (1,4-benzoquinone and 1,4-naphthoquinone) were identified in proxies of the...
Colton T Calvert

Oral anticoagulant (OAC) monotherapy vs. dual-antithrombotic therapy (DAT) in patients with atrial fibrillation and coronary artery disease; a meta-analysis of four randomized controlled trials

3 months ago
CONCLUSIONS: In patients with AF and stable CAD, OAC monotherapy reduced the risk of major bleeding, with no significant differences in NACE, major ischemic events, or all-cause mortality as compared to DAT.
Sufyan Shahid

Exploration of the mechanism and therapy of ovarian aging by targeting cellular senescence

3 months ago
The ovary is a crucial gonadal organ that supports female reproductive and endocrine functions. Ovarian aging can result in decreased fertility and dysfunction across multiple organs. Research has demonstrated that cellular senescence in various cell types within the ovary can trigger a decline in ovarian function through distinct stress responses, resulting in ovarian aging. This review explores how cellular senescence may contribute to ovarian aging and reproductive failure. Additionally, we...
Weicheng Tang

Exploring longitudinal associations between social determinants of health during adolescence and self-reported contraceptive use in young adulthood in the United States

3 months ago
CONCLUSIONS: A favorable environment during adolescence provides a foundation for positive health behaviors. Interventions aimed at improving contraceptive use in young adulthood should consider creating supportive environments for adolescents.
Shristi Bhochhibhoya

Transcatheter Mitral Valve Replacement With Atrial Fixation for Treatment of Atrial Functional Mitral Regurgitation

3 months ago
CONCLUSIONS: The AltaValve system shows promising early procedural and clinical results for the unique anatomy of patients with atrial functional mitral regurgitation. Long-term clinical studies to demonstrate the benefit of this system are warranted.
John T Saxon

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