BACKGROUND: Despite stroke being a leading cause of death in Pakistan, no study has comprehensively analyzed national and regional trends over time. This gap limits understanding of the evolving burden and underlying risk factors.

CONCLUSION: The Oklahoma Trauma Discharge Predictive Scoring Model demonstrated significant facility discharge prediction and may assist with decreasing delay of anticipated patient discharge destination.

Polygenic scores (PGSs) for body mass index (BMI) may guide early prevention and targeted treatment of obesity. Using genetic data from up to 5.1 million people (4.6% African ancestry, 14.4% American ancestry, 8.4% East Asian ancestry, 71.1% European ancestry and 1.5% South Asian ancestry) from the GIANT consortium and 23andMe, Inc., we developed ancestry-specific and multi-ancestry PGSs. The multi-ancestry score explained 17.6% of BMI variation among UK Biobank participants of European...

The use of in-feed antibiotics in livestock systems, particularly in poultry, has raised concerns about the increased prevalence of antibiotic-resistant human pathogens and the presence of antibiotic residues in animal products. Consequently, natural feed additives, including herbs and their bioactive compounds, are becoming preferred alternatives. Different species and varieties of mentha herbs contain varying essential oil components and concentrations, which influence their biological...

The Eulipotyphla (true insectivores) is the third largest mammalian order, comprising over 500 species, and could be an important source of human infectious diseases. However, relatively little is known about the microbial diversity in insectivores and their contribution to virus transmission among wild hosts. In this study, we compile a comprehensive dataset containing over 400,000 records of insectivores and their associated microbes from 1903 to 2023 from multiple public databases....