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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

imgResearchers

The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

imgProviders

The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

imgPatients

The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

TearCare system versus cyclosporine ophthalmic emulsion for the treatment of moderate-to-severe meibomian gland disease associated dry eye disease in the United States: a cost-utility analysis

3 months 2 weeks ago
CONCLUSIONS: TearCare is a cost-effective treatment for MGD-related DED, offering both clinical benefits and cost savings over CsA.
Nathan Lighthizer

Artificial intelligence in advanced practice nursing education: Opportunities and challenges

3 months 2 weeks ago
Artificial intelligence (AI) is transforming health care delivery and education, offering both opportunities and challenges. Because AI tools become more integrated into clinical practice, educators are exploring their potential to enhance learning, improve decision making, and prepare future providers for technology-rich environments. However, the use of AI in health care education raises concerns about academic integrity, overreliance, and the risk of AI-generated misinformation, known as...
Kimberly A Allen

The Ecological Genome Project and the Promises of Ecogenomics for Society: Realising a Shared Vision as One Health

3 months 2 weeks ago
This paper develops a vision for The Ecological Genome Project: an aspirational, global endeavour to connect human genomic sciences with the ethos of ecological sciences. The Project's goal is to strengthen interdisciplinary networks that relate to diverse initiatives using genomic technologies, with respect to shared ethical frameworks and governance structures. To this end, this paper proposes a practical definition of ecogenomics to align various methodologies and values in a single...
Benjamin Capps

'Knowing and Treating Kosaki/Penttinen syndrome' international collaborative consortium: recommendations for follow-up, natural history and a real-life observational study about safety and efficacy profile of tyrosine kinase inhibitors

3 months 2 weeks ago
CONCLUSION: The consortium welcomes new teams on an ongoing basis. Recommendations are especially useful in such ultra-rare degenerative diseases. The real-life observational study seems to be an appropriate model to improve knowledge, including the assessment of treatment efficacy when the prevalence of the disease does not allow the setting up of clinical trials.
Yordi-Michaël Bouhatous

Functional and transcriptomic profiling of bovine circulating neutrophils during in vitro lipopolysaccharide challenge across different energetic states

3 months 2 weeks ago
Polymorphonuclear neutrophils are pivotal players in the innate immune response of dairy cows. Their functionality (phagocytosis [PC] and oxidative burst [OB]) and gene expression patterns, however, can be modulated by varying energetic conditions. Energetic fluctuations are particularly evident in periparturient dairy cows, when distinct levels of negative energy balance can trigger PMN dysfunction. This study aimed to assess how different energetic conditions affect PMN functionality and to...
Lei Xie

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