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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

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The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

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The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Relationships among discrimination, cognitive-affective pain amplifiers, and identification with Native American culture: results from the Oklahoma Study of Native American Pain Risk

2 months 2 weeks ago
CONCLUSIONS: These findings suggest that the relationship between discrimination and pain catastrophizing is stronger for NAs who identify more strongly with NA culture, an effect that is likely due to these individuals having greater overall exposure to discrimination. Alternatively, the NAAS may not capture the full range of cultural processes that buffer against negative health outcomes for NAs. Future research should examine other facets of cultural resilience.
Brandon W Jones

TIPS to Treat Chylous Ascites due to Cirrhosis

2 months 2 weeks ago
Chylous ascites is a rare form of ascites that arises from the disruption of lymphatic flow. It develops in patients with liver cirrhosis secondary to portal hypertension. Treatment options include dietary modifications, pharmacological agents, and procedural interventions. Transjugular intrahepatic portosystemic shunt (TIPS) placement has been proposed as a treatment option for chylous ascites in decompensated liver cirrhosis. Our case report discusses a patient with decompensated liver...
Muhammad Amir

Interface Catalysts of In Situ-Grown TiO<sub>2</sub>/MXenes for High-Faraday-Efficiency CO<sub>2</sub> Reduction

2 months 2 weeks ago
Climate change and the global energy crisis have led to an increasing need for greenhouse gas remediation and clean energy sources. The electrochemical CO(2) reduction reaction (CO(2)RR) is a promising solution for both issues as it harvests waste CO(2) and chemically reduces it to more useful forms. However, the high overpotential required for the reaction makes it electrochemically unfavorable. Here, we fabricate a novel electrode composed of TiO(2) nanoparticles grown in situ on MXene charge...
Shaun Debow

1<em>H</em>-Indoles from Deoxybenzoin Schiff Bases by Deprotonation-S<sub>N</sub>Ar Cyclization

2 months 2 weeks ago
A transition metal-free synthesis of 1,2,5-trisubstituted 1H-indoles by a deprotonation-S(N)Ar cyclization sequence from 1-aryl-2-(2-fluoro-5-nitrophenyl)ethan-1-one (deoxy-benzoin) Schiff bases is reported. The starting deoxybenzoins were prepared by Friedel-Crafts acylation of activated aromatic compounds by 2-(2-fluoro-5-nitrophenyl)acetyl chloride with AlCl(3) or the corresponding acid with (CH(3)SO(2))(2)O. The Schiff bases were generated by slow distillation of toluene (18-24 h) from a...
Nash E Nevels

Serum and Skin Carotenoid Levels in Older Adults with and Without Metabolic Syndrome: A Cross-Sectional Study

2 months 2 weeks ago
Introduction: Metabolic syndrome (MetS), a clustering of cardiovascular disease (CVD) risk factors, is associated with increased mortality. Fruit and vegetable (FV) intake is inversely associated with CVD risk, and carotenoids, bioactive compounds found in brightly colored FVs, can be measured in serum and skin as biomarkers of intake. While serum and skin carotenoids are correlated in healthy populations, this relationship is not well understood in older adults with MetS, who may have altered...
Susan Veldheer

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