CONCLUSIONS: Our findings suggest that anthrax toxins contribute to the exacerbation of pathological host responses during anthrax sepsis, including coagulopathy, complement activation, endothelial dysfunction, and organ injury. These observations provide insight into the role of toxins in intensifying disease severity beyond bacterial burden alone. Therapeutic strategies targeting coagulation and complement pathways and preserving endothelial function may help mitigate anthrax-induced sepsis.

CONCLUSIONS: Our results suggest that different drivers best influence different classes of Orthoebolavirus outbreaks, and that models taking into account a variety of factors are needed to predict future spillover events.

Root system architecture affects water and mineral uptake and is important for plant adaptation to fluctuating nutrient availability. Several small signaling peptides and their cognate receptors are known to influence root physiological and morphological traits associated with macronutrient uptake. In the current study, genome-wide association studies were performed using 2-D images of agar plate-grown Medicago truncatula accessions to understand the impact of GOLVEN10 peptide (GLV10) treatment...

CONCLUSIONS: Colostrum-derived BVDV antibodies suppressed BVDV detection in PI calves during the first week of life, leading to false-negative results with various sample types and tests.

Carbon nanotubes (CNTs) have garnered considerable interest in dentistry due to their exceptional properties, including high tensile strength (TS), low weight, chemical stability, and antimicrobial activity. These attributes make CNTs valuable for enhancing the mechanical performance and therapeutic potential of dental materials. Recent advances have demonstrated their effectiveness in dental composites, improving flexural strength (FS), wear resistance, and minimizing polymerization shrinkage....