CONCLUSION: Analysis of the ClinicalTrials.gov data permits summarization of the current scope of interventional knee injury trials. The unique techniques being developed currently can help guide physicians looking to implement new interventions into their practices. They can also provide insight into the advancement of interventional clinical trial setup and execution regarding knee injuries, as well as save both patients and insurance companies money in the long term.

We present draft genomes of Citrobacter freundii strains isolated from a model wastewater treatment plant seeded with sludge from Stillwater, Oklahoma. Analysis suggests that the Stillwater strains are related to human isolates from China and the UK. All strains also possess antimicrobial resistance genes, highlighting the potential public health implications.

CONCLUSIONS: Behaviors such as night waking can be a normative part of early development for toddlers without developmental concerns. Findings from our study may be useful for helping families set realistic expectations about their child's sleep during toddlerhood.

Efforts to improve the work environment are supported by nurse scientists (NSs), doctorally prepared researchers who conduct, facilitate, and promote research in health care organizations. While decades of research demonstrate the value of assessing and benchmarking clinician work environments, the nursing profession struggles to create and maintain healthy workplaces. Recognizing the need for improvement, national organizations have called for the advancement and promotion of healthy work...

Epilepsy is a chronic neurological disorder marked by recurrent, unprovoked seizures that can lead to cognitive impairment, psychiatric comorbidities, and reduced quality of life. While seizure control is critical for minimizing long-term neurological harm, conventional antiseizure medications (ASMs) are often hindered by limited brain penetration, systemic toxicity, and pharmacoresistance. Liposomal drug delivery systems offer a promising approach to overcome these limitations by enhancing...