BACKGROUND: Traditional nursing delegation frameworks treat care tasks as discrete, isolated units, failing to reflect the complex realities of contemporary nursing practice.

Genomic imprinting is an epigenetic mechanism in which gene expression is determined by the parent of origin. Imprinted genes are crucial for mammalian growth and development, and mutations at imprinting sites can lead to developmental disorders and diseases. Therefore, identifying novel imprinted differentially methylated regions (DMRs) is essential for understanding imprinting mechanisms and their implications in human biology. This study aimed to identify new imprinted DMRs using...

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Emphysematous osteomyelitis (EOM) is a rare and severe subtype of osteomyelitis where infection potentiates free air into surrounding bone. Existing literature is limited, but diabetes mellitus and malignancy are described as major risk factors. We report a patient that presented with multiple perianal abscesses and was diagnosed with an advanced rectal adenocarcinoma. He was treated with abscess drainage, antibiotics, and diverting colostomy. Several weeks later he was readmitted in septic...

MRI studies in bipolar disorder (BD) have yielded inconsistent findings, partly due to the varied use of psychotropic medications. This study utilised a mega-analysis approach, accounting for concurrent medication status (syndrome-based and Neuroscience-based Nomenclature (NbN) classifications), in order to assess the association of medication status with subcortical brain volumes in BD. Data from 2,664 BD patients and 4,065 controls (CN) were pooled from 34 research groups as part of the ENIGMA...