For winter wheat in the US Central Great Plains, phenotypic plasticity of yield is agronomically adaptive, i.e., genotypes with higher plasticity have higher yield in high yielding environments with no tradeoff in stressful, low yielding environments. Using data from variety trials conducted between 2000 and 2022 and cultivars released between 1991 and 2022, we explored time trends in phenotypic plasticity and heritability of yield. Given that yield plasticity is agronomically adaptive in the...

CONCLUSION: This study is among the first to identify specific associations between firearm-related risk behaviors and distinct polysubstance use trajectories. The findings provide novel insights for developing targeted interventions to mitigate firearm risks in polysubstance-using individuals transitioning from adolescence to young adulthood.

To develop radiomics models based on baseline multi-parametric magnetic resonance imaging (MRI) data and clinical characteristics to predict 6-month progressive disease (PD) status in metastatic gastrointestinal stromal tumor (GIST) patients receiving targeted therapy, enabling long-term prognostication for early stratification of high-risk mortality groups. Eighty-eight metastatic GIST patients undergoing targeted treatment were included in this study and randomly divided into a training cohort...

CONCLUSIONS: Parathyroidectomy was associated with significantly lower rates of new-onset neuropsychiatric disorders in patients with primary hyperparathyroidism compared with medical management.

The objective of this study was to compare coronavirus disease 2019 (COVID-19) and influenza among US active-component service members (ACSMs) stationed at military installations near the US-Mexico border (Arizona, California, New Mexico, and Texas). A retrospective cohort study was conducted to assess diagnoses of influenza (2020-2024) and COVID-19 (2020-2023). Incidence rate ratios (IRRs) comparing influenza and COVID-19 at border and non-border locations were calculated for...