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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

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The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

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The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Lithium and cobalt recovery from petroleum produced water using dolomite: impact of pH, temperature, and surface area

2 months 1 week ago
Batch reaction experiments were conducted to determine the feasibility and to elucidate the mechanics of lithium and cobalt recovery from petroleum produced water (PW) using dolomite. The results demonstrate that dolomite effectively recovers high concentrations of Li^(+) and Co^(2+) (100 mg/L) from PW even in the presence of several competing metal cations. Additionally, the results support a surface reaction mechanism in which sorbed Co^(2+) and Li^(+) ions onto dolomite surface form carbonate...
Marwa Elshebli

Assessing genetic gain and diversity in Ethiopian bread wheat across six decades

2 months 1 week ago
Assessing breeding progress and genetic diversity in released varieties is crucial for informing future crop improvement strategies. This study evaluated genetic gain and diversity in 49 Ethiopian wheat varieties released over six decades (1967-2021). Significant yield increases were observed, with 'Shaki' showing the highest gain. However, the average annual genetic gain was modest (0.90% under irrigated, 0.69% under rain-fed). The recent released bread wheat variety ″Shaki″ exhibited a 48.6%...
Sefawdin Berta

APOA1 binding protein promotes lymphatic cell fate and lymphangiogenesis by relieving caveolae-mediated inhibition of VEGFR3 signaling

2 months 1 week ago
The lymphatic system maintains tissue fluid balance, and its dysfunction can result in lymphedema. Although cholesterol is essential for cellular function, its role in lymphatic development has remained unknown. Here, we identify APOA1 binding protein (AIBP) as a key regulator that promotes lymphatic endothelial cell fate specification and lymphangiogenesis. Mechanistically, AIBP reduces plasma membrane cholesterol content, thereby enhancing VEGFR3 signaling by disrupting caveolae-small plasma...
Jun-Dae Kim

Review of Thelastoma Leidy, 1849 (Nematoda: Oxyuridomorpha: Thelastomatidae) and description of T. variabile sp. nov. from the North American indigenous millipede Narceus americanus (Spirobolida: Spirobolidae)

2 months 1 week ago
Thelastoma variabile sp. nov. (Nematoda: Oxyuridomorpha: Thelastomatoidea) is described from the intestine of 82 specimens of the Narceus americanus/annularis complex (Diplopoda: Helminthomorpha: Spirobolidae) collected from April through October 2021 in Hochatown, McCurtain County, Oklahoma, U.S.A. A total of 343 T. variabile sp. nov. consisting of 315 females, 1 male and 27 juveniles were extracted primarily from the hindguts of the millipedes. Examination of the new species was conducted with...
Gary Phillips

Conservation, systematics and ultrastructure of the poorly known amblypygid species Charinus santanensis (Charontidae, Amblypygi) from Caatinga caves in Brazil

2 months 1 week ago
Charinus is the most speciose genus of the Charontidae, with the highest number of species in Brazil (43 spp). Almost half of these species are known to inhabit caves, a fragile ecosystem that is little known and is highly threatened by human activities. Eleven of the Brazilian species of Charinus occur only inside caves (troglobionts) being, therefore, an important component of cave ecosystems acting as one of the major cave predators. Here, we discuss conservation priorities and concerns for...
Williams Paredes Munguia

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