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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

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The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

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The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Competency and Confidence in Qualitative Biomechanical Assessment of Exercise Technique Among Exercise Professionals

2 months 1 week ago
Petushek, E, Breen, S, Myer, GD, Dupuis, BP, Dorgo, S, Ebben, W, and Krosshaug, T. Competency and confidence in qualitative biomechanical assessment of exercise technique among exercise professionals. J Strength Cond Res XX(X): 000-000, 2025-Understanding resistance exercise technique is critical for exercise professionals, but research on this as a specific competency is lacking. This study evaluated resistance exercise technique analysis competency, confidence, and perceived importance in a...
Erich Petushek

Adipose cullin 3 mediates the antiobesity effect of pan neddylation inhibitors

2 months 1 week ago
Cullin Ring E3 Ligases (CRLs) belong to the largest family of multisubunit ubiquitin E3 ligases. A cullin serves as the scaffold protein that recruits E3 ligases and substrate receptors in a CRL complex, whose activity requires cullin neddylation, a posttranslational modification that can be pharmacologically targeted by neddylation inhibitors. Elevated neddylation activity has been observed in the liver and adipose tissue of obese mice, implicating a pathogenic link between altered CRL activity...
Lijie Gu

Baseline use of aspirin or statins with oral estrogen and progestogens to prevent incident arterial or venous thrombotic events: a secondary analysis of the Women's Health Initiative trial

2 months 1 week ago
CONCLUSIONS: In this secondary randomized clinical trial analysis, neither statins nor aspirin significantly modified effects of oral HT on key arterial or venous thrombotic outcomes at 2 or 5 years. Results, however, may be underpowered given low baseline exposure prevalence for both statins and aspirin.
John W Davis

25-Hydroxycholesterol restricts human norovirus replication in human intestinal enteroids

2 months 1 week ago
Norovirus is the leading cause of acute gastroenteritis worldwide. Since the development of human intestinal enteroid (HIE) cell culture systems, significant advancements have been made in exploring and evaluating therapeutic strategies to combat human norovirus infections. Here, we investigate whether 25-hydroxycholesterol (25-HC), a key regulator of cholesterol homeostasis and bile acid production, can restrict human norovirus replication in jejunal HIE monolayers. Jejunal HIE monolayers...
Verónica Costantini

"As a resistor, you are not alone": Locating the collective in uncoordinated acts of professional resistance

2 months 1 week ago
INTRODUCTION: When trainees encounter social harm and injustice in clinical and educational settings, they engage in acts of professional resistance. These efforts can either be coordinated or uncoordinated and implemented as individuals or collectives. Although it is easy to see the relationship between the collective and individuals in coordinated acts, it is unclear what role a collective plays in uncoordinated resistance efforts. This study investigated the role of a larger collective,...
Tasha R Wyatt

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