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CONCLUSIONS AND INFERENCES: TEA at acupuncture points ST36 and PC6 with appropriate parameters is effective in treating the major gastrointestinal symptoms in patients with diabetic gastroparesis. Further pivotal studies are warranted to determine its clinical efficacies.

Recent evidence suggests that cellular metabolism, including glycolysis and fatty acid synthesis in lymphatic endothelial cells (LECs), plays essential roles in developing functional lymphatic systems. Site-1 protease (S1P) proteolytically activates membrane-bound latent transcription factor sterol regulatory element-binding proteins (SREBPs), which are required to induce lipid biosynthesis. In this study, we generated mice with pan-endothelial or LEC-specific deficiency of either S1P or SREBP2....

Peptide-based hydrogels stimulate stem cell differentiation into neurons, improve neuroprotection, and aid in spinal cord/brain injury repair by moderating inflammatory responses and activating endogenous healing pathways. Peptoid-based hydrogels, with superior enzymatic stability and tunable properties, offer a promising alternative but remain unexplored in neurodegenerative therapies. Thus, future study should focus on optimizing peptoid-based hydrogel formulations, which could considerably...