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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

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The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

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The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Evaluation of Long-Term Performance of Six PM<sub>2.5</sub> Sensor Types

3 months 1 week ago
From July 2019 to January 2021, six models of PM(2.5) air sensors were operated at seven air quality monitoring sites across the U.S. in Arizona, Colorado, Delaware, Georgia, North Carolina, Oklahoma, and Wisconsin. Common PM sensor data issues were identified, including repeat zero measurements, false high outliers, baseline shift, varied relationships between the sensor and monitor, and relative humidity (RH) influences. While these issues are often easy to identify during colocation, they are...
Karoline K Barkjohn

Access to Substituted Tricyclic Heteroarenes by an Oxidative Cyclization Reaction and Their Antifungal Performance

3 months 1 week ago
Background/Objectives: Fungal pathogens are increasingly developing concerning resistance against the currently available antifungal drugs, which creates a constant demand for new antifungal agents. Methods: Here, we report the synthesis of C3,N4-substituted triazole derivatives containing a N4-(2-((4-methoxybenzyl)thio)phenyl) group. By selectively removing the 4-methoxybenzyl group, we were able to access the free thiol analogs which, under oxidative conditions, undergo a cyclization reaction...
Rehema Nakiwala

Unveiling Tick Diversity in Cattle in Cameroon: Emergence of <em>Rhipicephalus microplus</em>, Replacing the Original <em>Rhipicephalus</em> spp

3 months 1 week ago
Ticks are well-known vectors of pathogens, posing considerable risks to livestock health and productivity. In Cameroon, where livestock production is vital, established tick species such as Amblyomma variegatum and Hyalomma truncatum are prevalent in key cattle-rearing areas. The recent introduction of the invasive, acaricide-resistant Rhipicephalus microplus further complicates control efforts. In this study, we deliver baseline data on the composition of tick species and their shifts within...
Muhammad Umair Aziz

Chromatin Remodulator CHD4: A Potential Target for Cancer Interception

3 months 1 week ago
Cancer initiation and progression are associated with numerous somatic mutations, genomic rearrangements, and structure variants. The transformation of a normal cell into a cancer cell involves spatio-temporal changes in the regulation of different gene networks. The accessibility of these genes within the cell nucleus is manipulated via nucleosome remodeling ATPases, comprising one of the important mechanisms. Here, we reviewed studies of an ATP-dependent chromatin remodulator, chromodomain...
Krishnendu Goswami

Outcomes of Robot-Assisted Transbronchial Biopsies of Pulmonary Nodules: A Review

3 months 1 week ago
Background/Objectives: Robot-assisted bronchoscopy (RAB) is a novel platform for sampling peripheral pulmonary nodules (PPNs). To further clarify the role robot-assisted platforms have in diagnosing PPNs, we performed a review of the recent literature. Methods: A systematic review was performed in Medline from 2019 to 2024 using the search terms "robotic bronchoscopy", "diagnostic yield", "sensitivity", and "positive predictive value", alone and in combination. Studies that focused on earlier...
Peter A Ebeling

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