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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

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The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

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The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Interoception, Immunoception, and the Role of Insular Cortex in Cardiovascular Disease

1 month 3 weeks ago
Whereas the brain-heart axis is an emerging field in neuropsychocardiology, a central autonomic network including the insular cortex (Ic) regulates the cardiovascular system via the intrinsic cardiac nervous system. Cardiac interoception, represented in Ic, has been studied in cardiovascular diseases and inflammation. Therefore, it is important to investigate how interoception is related to cardiovascular disease in terms of its prevention and treatment. To examine the role of the Ic in...
Michiaki Nagai

Multimodal support for cardiorespiratory failure from paradoxical coronary and pulmonary embolism: A case report of mechanical support, revascularization, embolectomy, and shunt closure

1 month 3 weeks ago
Paradoxical coronary embolism (PCE) is an uncommon cause of acute myocardial infarction (AMI), typically occurring when venous thromboemboli cross a right-to-left shunt in the setting of elevated right-sided pressures. We report a case of mixed obstructive and cardiogenic shock caused by simultaneous pulmonary embolism (PE) and PCE. A previously healthy 43-year-old woman developed profound hypoxemia and inferior ST-segment elevation 3 days after knee surgery. Coronary angiography revealed distal...
Casey Carr

Extracorporeal life support in lung transplantation with dual-lumen cannulas: A systematic review

1 month 3 weeks ago
BackgroundRefractory end-stage lung failure may benefit from extracorporeal life support (ECLS) as a bridge to lung transplantation. Venovenous (VV) extracorporeal membrane oxygenation (ECMO) is indicated in patients who have failed conventional medical treatment and mechanical ventilation. The Avalon Elite Bi-Caval Dual-Lumen Catheter (Getinge) and the Crescent Jugular Dual-Lumen Catheter (MC3, Inc., Medtronic) have been used for this configuration. Venoarterial (VA) ECMO may be used in...
Massimo Capoccia

Hybrid venoarteriopulmonary extracorporeal membrane oxygenation for severe respiratory failure and refractory right ventricular injury: A case report

1 month 3 weeks ago
IntroductionExtracorporeal membrane oxygenation (ECMO) provides lifesaving support for severe respiratory and cardiac failure. Hybrid modes such as venoarteriopulmonary (VAP) may be necessary when conventional modes fail to meet complex physiological demands.Case ReportA 31-year-old woman with dermatomyositis-associated interstitial lung disease developed severe respiratory failure. She was initiated on venovenous (VV) ECMO, later complicated by right ventricular injury (RVI) requiring...
Joseph M Brewer

Inequities in the compliance of court-ordered point-of-sale tobacco industry corrective statements, USA

1 month 3 weeks ago
INTRODUCTION: In 2006, a federal US court found several major tobacco companies guilty of violating civil racketeering laws for deceiving the public about the harms of cigarettes. After 16 years of legal battles, the court ordered 17 corrective statements to be placed in over 200 000 tobacco retailers who have contracts with the tobacco companies to educate the public on the truth about tobacco-related harms. This study examined if corrective statement compliance was equitable across...
Amanda Y Kong

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