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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

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The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

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The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Genomic prediction via reaction norm models for pregnancy loss using temperature humidity index in brahman cattle

2 weeks 3 days ago
Brahman cattle are widely used in tropical production systems due to their adaptability; however, reproductive efficiency remains constrained by pregnancy loss (PL), particularly under heat stress. This study evaluated genotype-by-environment (G × E) interactions for PL using reaction norm models incorporating the temperature-humidity index (THI) as an environmental descriptor. Records from Brahman heifers in two Bolivian herds were combined with weather data to calculate accumulated THI for the...
Daniel Cardona-Cifuentes

Zinc-based cyclens containing pyridine and cross-bridges: X-ray and DFT structures, Lewis acidity, gas-phase acidity, and p<em>K</em> <sub>a</sub> values

2 weeks 3 days ago
It is well known that catalytic centers containing the zinc(II) ion can act as both Lewis and Bronsted-Lowry acids. In addition to coordination number, the Zn coordination geometry can also strongly impact the acidity of the active site, no matter what measure of acidity is considered. Herein, we report the first pentacoordinate, zinc-ammonia complex containing a pyridine based tetraazamacrocycle, [(pyclen)Zn(NH(3))](PF(6))(2), that has applications in Lewis acid catalysis. From this structure,...
Douglas P Linder

Pregnancy as a journey of care and connection: Indigenous women's experiences navigating health systems and community support

2 weeks 3 days ago
INTRODUCTION: Pregnancy and childbirth are opportunities for Indigenous communities to welcome new life, integrate meaningful cultural practices, and tangibly strengthen communal wellbeing. Simultaneously, pregnant American Indian and Alaska Native (AIAN) women must navigate complex healthcare systems while experiencing structural inequities that contribute to elevated risks of complications and poor birth outcomes. This study explored the pregnancy experiences of AIAN women, examining how...
Christina M Pacheco

Ancient hybridization and phylogenetic discordance: Exploring evolutionary complexity in Asteraceae

2 weeks 3 days ago
PREMISE: Conflicting phylogenetic signals are common in plant phylogenomics and often reflect evolutionary histories shaped by processes like hybridization, incomplete lineage sorting, and whole-genome duplication (WGD). We aimed to identify and assess these complex processes in the hyper-diverse family Asteraceae to offer insight into the underlying causes of phylogenetic discordance.
Paige A Ellestad

Alternative Splicing of Rice Chloroplastic CuZn Superoxide Dismutase, OsCSD2: Impact on expression and protein characteristics

2 weeks 3 days ago
Superoxide dismutases (SODs) are involved in cellular reactive oxygen species (ROS) homeostasis under diverse conditions. Among different plant SODs, CuZnSODs (CSDs) are most abundant and localized to multiple compartments, including chloroplast. Rice (Oryza sativa) genome encodes a chloroplastic CuZnSOD (OsCSD2, LOC_Os08g44770), which undergoes alternative splicing (AS), generating two splice variants (SVs), OsCSD2-SV1 (constitutive) and OsCSD2-SV2 (alternative). The AS-event remove 12...
Ravi Prakash Sanyal

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