This review highlights major advances in neurogastroenterology since Rome IV, offering a condensed summary of a comprehensive document to appear in the forthcoming Rome V book. Prepared by an international team of experts, it emphasizes pivotal studies that have deepened understanding of the physiological and pathophysiological mechanisms underlying disorders of gut-brain interaction (DGBI). These disorders are inherently complex and multifactorial, shaped by interactions among neuronal,...

CONCLUSIONS: AB-Real provides the first global real-world evidence of long-term efficacy of A+B in uHCC. Long-term survivorship is enhanced in radiological responders and strongly associated with pre-treatment tumor factors and liver function.

Background: There is substantial care variation for children with croup. Our primary aim was to describe variation in croup pathways by acute care setting and hospital type among sites participating in a national quality improvement (QI) collaborative: Better Assessment and Response to Croup in Kids (BARCK).Methods: We conducted a cross-sectional study, consisting of site surveys to identify site characteristics and independent review of croup clinical pathways by study physicians. Site...

CONCLUSIONS: Individuals may demonstrate higher CMAS scores during planned than unplanned movement conditions. However, the differences in movement quality across conditions may be influenced by additional variables, such as approach velocity and stimulus timing. Collegiate division may not significantly affect movement quality in collegiate female basketball players.

Bovine viral diarrhea virus (BVDV) strains of differing virulence are associated with distinct clinical and lymphoid outcomes, but transcriptional responses within peripheral lymphocyte compartments remain incompletely defined. Here, we performed RNA-seq on CD4/CD8β/TcR1 bead-enriched peripheral lymphocyte fractions from calves experimentally infected with low-virulence or high-virulence noncytopathic BVDV strains (BVDV2-RS886 and BVDV2-1373, respectively) and sampled at days 0, 3, and 15 days...