CONCLUSION: We identified corroborated changes in metabolome after AIS across different technologies and study designs. These changes correspond to loss of nerve cell membrane integrity and activation of alternative metabolic pathways in the setting of blood brain barrier (BBB) disruption. If proven on a larger sample, our findings may improve prediction of mortality, and functional outcomes after AIS.

Quantifying thermodynamics, structural, and dynamical properties of brine confined in clay pores is critical for a variety of geo-energy applications, including underground hydrogen storage (UHS) and carbon capture and sequestration (CCS). Atomistic molecular dynamics simulations are applied here to study aqueous NaCl brines within 10-Å kaolinite slit pores. NaCl concentrations are chosen at 5, 10, 12.5, and 15 wt. %, all below the solubility limit and high enough to provide statistically...

Risk perceptions of energy systems, and their evolution under climate change and after accidents, affect public acceptance of generation technologies. Despite this, little is understood about how such factors impact public perception at different timescales and the drivers for perception. We use state-of-the-art natural language processing to measure temporal changes in sentiment toward energy technologies using the full Twitter archive for 2009-2022. We find that perception of natural gas and...

No abstract

We report a rare case of atypical fibroxanthoma (AFX)-like melanoma on the scalp of a 75-year-old man. A biopsy of an erythematous, tender nodule on the left posterior parietal scalp revealed an ulcerated nodular lesion composed of epithelioid and spindle cells with pleomorphic nuclei arranged in a fascicular pattern. The tumor's architectural and cytologic features, including the presence of an epidermal collarette, marked anisonucleosis, and numerous atypical mitoses, closely resembled those...