CONCLUSIONS: Our results show that GPx4 overexpression protected muscle mass and mitochondrial respiration in tumour-bearing mice, possibly by reducing muscle inflammation. Future studies will explore the potential mechanisms for the protective effect of GPx4 in cancer cachexia.

No abstract

No abstract

Musth, a hormonally driven state characterized by increased testosterone, aggression, and physiological changes, poses significant management challenges for male Asian elephants (Elephas maximus) in zoos. Immunological castration, a nonsurgical method using anti-GnRH immunotherapeutic (Improvest®), offers a promising tool to suppress musth. This case study documents the behavioral and physiological effects of immunological castration in a 54-year-old male Asian elephant at the Oklahoma City Zoo...

No abstract