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CONCLUSIONS: Post-COVID shifts toward HFRT were associated with higher RT completion and reduced disparities, suggesting more efficient and equitable treatment delivery of adjuvant breast RT.

The Kidney Disease Outcomes Quality Initiative (KDOQI) convened a work group to review the 2025 KDIGO (Kidney Disease: Improving Global Outcomes) clinical practice guideline for the evaluation, management, and treatment of autosomal dominant polycystic kidney disease (ADPKD). The KDOQI work group reviewed the KDIGO guideline statements and practice points and provided perspective for implementation within the context of clinical practice in the United States. In general, the KDOQI work group...

The assessment of body composition has long been a fundamental component of research and is gaining increasing adoption in clinical practice. This growing interest has drawn new professionals to the field and increased emphasis on its clinical relevance and applications. However, the diversity of assessment techniques and inconsistent terminology create challenges, highlighting the urgent need for harmonized approaches across research and healthcare settings. Commonly employed methods include...

Interventions Testing Program identified rapamycin as a robust lifespan-extending agent at multiple testing sites and in both sexes, with particularly strong effects in females, making it a leading candidate in aging research. We used genetically heterogeneous UM-HET3 mice of both sexes to determine whether rapamycin can prevent or delay age-sensitive traits. Mice were supplemented with microencapsulated rapamycin at 14 ppm starting at 12 months of age. Chronic rapamycin supplementation...