CONCLUSIONS: Quantitative immunoglobulin levels and naïve T cells remain valuable indicators of IEI in AIC. Our findings highlight the diagnostic value of emerging cellular and serum biomarkers in identifying IEI, including dysregulation of early B-cell subsets (transitional B cells and CD19^(hi)CD21^(lo) B cells), expansion of T(FH) cells, and elevated levels of BAFF and sIL2R.

Asian Americans are often stereotyped as model minorities-hardworking (achievement aspect) and unaffected by socioeconomic barriers (mobility aspect). However, the impact of these stereotypes on mental health remains unclear. This study is the first to examine longitudinally how internalizing these stereotypes relates to mental health, as moderated by grade point average (GPA), parental education, and household income among Asian American subgroups. Using a three-wave panel study of 610 Filipino...

The Surpass flow diverter, including Streamline and Evolve, features a unique design optimized for improved conformability, opening, and wall apposition. Its unique pore structure allows for deployment across a wide range of arterial diameters, contributing to its high occlusion rates. The current study aims to compare the efficacy and safety of the Surpass Streamline and Evolve in treating intracranial aneurysms, with a focus on location, size, and morphology. A systematic review and...

CONCLUSIONS: In this large cohort of EP-CT participants, most patients received supportive care services and had documented ACP, suggesting trial-related engagement does not impede care delivery. Notably, receipt of supportive care services correlated with ACP documentation. These findings underscore the importance of addressing individual supportive care needs among EP-CT participants.

No abstract