Large language models (LLMs) have demonstrated impressive proficiency in various science and engineering applications. However, due to the innate multi-scale property of biological systems, existing LLMs face severe limitations in capturing hierarchical relationships and context-dependent interactions across molecular, cellular, tissue, and systemic levels. These models often lack the architectural mechanisms needed to reason effectively across different biological scales, resulting in reduced...

Pride In All Who Served (PRIDE) is the first manualized, evidence-based group intervention developed for lesbian, gay, bisexual, transgender, queer, intersex, asexual, and/or other diverse sexual/gender identities (LGBTQIA+) Veterans. PRIDE has spread to over 70 Veterans Administration Medical Centers (VAMCs) in every region of the country and continues to scale to new sites. In 2023, a PRIDE Manual Revision Team was formed to create a new version of the PRIDE Facilitation Manual (Version 3)...

CONCLUSION: These real-world clinical practice data indicate a decline in the use and duration of oral anticoagulation for acute cervical artery dissection.

Pediatric intracranial aneurysms are rare and challenging to manage due to the delicate nature of developing cerebrovasculature. Traditional neurosurgical approaches pose significant risks, particularly in infants. Reconstructive neuroendovascular techniques such as flow diversion have excellent outcomes in the adult population, although data in children are limited. This case report details use of a flow diverting stent in a 12-month-old male presenting with spontaneous subarachnoid hemorrhage...

CONCLUSIONS: This study underscores the importance of identifying and addressing gaps between organizational policies or standard operating procedures and actual practices while engaging frontline staff. The implementation of new medication lockboxes significantly improved the medication storage process, demonstrating the effectiveness of quality improvements methods in enhancing both safety and efficiency. These findings highlight the value of a collaborative, systems-based approach in driving...