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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

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The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

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The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Fundamental kinetic and selectivity properties of the anti-aging, antioxidant-active ingredient EUK-134

2 months 2 weeks ago
EUK-134 is a manganese-salen complex, derived from the parent molecule EUK-8, and is widely used in anti-aging skincare formulations because of its potent antioxidant activity, resulting from the catalytic decomposition of reactive oxygen species (ROS). Despite this popularity, the fundamental kinetic properties (k) that govern its efficacy and overall recyclability are not well understood, limiting the understanding of its behavior and further optimization in skincare products and therapeutic...
Nora Del Bosque

Tuning thermodynamics and electronic properties of 1-hexyl-3-methylimidazolium based organic ionic liquids with iron porphyrin

2 months 2 weeks ago
Ionic liquid-iron porphyrin (IL-FeP) complexes are systems with diverse applications, particularly in oxygen reduction reactions and the biodegradation of ionic liquids by cytochrome P450 enzymes, where FeP serves as the active site. Despite the importance of such systems, there is currently a lack of information on the conformational preference of ionic liquids binding to FeP and the influence that such binding conformations exert on the electronic properties of FeP. In addition, the role of...
Sudip Kumar Das

A bi-stage data-driven process-based model for sorghum breeding and yield prediction: coupling explainable artificial intelligence and crop modeling

2 months 2 weeks ago
With the global population explosion, the increasing demand in food supply pushes the development of advanced breeding methods. This study presents a bi-stage data-driven and process-based crop model to provide breeding recommendations based on Genotype x Environment (GxE) effects for sorghum, a vital cereal crop with various plant types, such as Grain (G), Forage (F), Dual Purpose (DP), and Photoperiod-Sensitive (PS). The model combines traditional process-based crop modeling with explainable...
Zheng Ni

Liquid-liquid phase separation-driven molecular subtyping and prognostic modeling in colorectal cancer

2 months 2 weeks ago
CONCLUSIONS: An LLPS-related prognostic model was created, enabling the stratification of the CRC population according to risk and informing individualized therapeutic strategies.
Hui Guan

Pigeons' choosing to go to work: Using reinforcement-based methods to balance animal welfare with research needs

2 months 2 weeks ago
We arranged conditions of social enrichment for a group of six pigeons as part of a larger program of research concerned with an animal model of gambling. When not in their experimental sessions, the pigeons lived together in a free-flying aviary, interacting with each other and with a physical environment that included perches, nesting materials, and nesting boxes. This enabled a range of species-typical social behavior including courtship, mating, and reproductive behavior. To minimize human...
Cyrus F Kirkman

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