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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

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The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

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The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

imgPatients

The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Dissecting Aneurysm in Cervical Artery Dissection: Insights from the STOP-CAD Study

2 months 2 weeks ago
Background: Cervical artery dissection (CeAD) may result in dissecting aneurysm (DA) formation. We aimed to characterize risk factors and clinical outcomes associated with DA in a large, international CeAD cohort. Methods: We performed a secondary analysis of the Antithrombotic Treatment for Stroke Prevention in Cervical Artery Dissection (STOP-CAD), an international, multicenter, retrospective cohort. Patients with spontaneous CeAD were assessed for DA at baseline and de novo DA formation....
Muhib Khan

Characterizing Particulate Matter Impacts of Smoke From 2022 to 2023 Agricultural Burning in South Florida

2 months 2 weeks ago
Smoke from agricultural fires is a potentially important source of fine particulate matter (PM(2.5)) in the US. Sugarcane is burned in Florida to facilitate the harvesting process, with the majority of these fires occurring in the Everglades Agricultural Area (EAA), where there is only one regulatory air quality monitor. During the 2022-2023 sugarcane burning season (October-May), we used public low-cost PurpleAir sensors, regulatory monitors, and 29 PurpleAir sensors deployed for this study to...
Olivia Sablan

Temperature-driven reaction pathways in alkane direct dehydrogenation over metal-free nitrogen doped carbocatalysts

2 months 2 weeks ago
Metal-free heteroatom-doped carbocatalysts are promising alternatives to precious metals for alkane direct dehydrogenation/hydrogenation and reversible hydrogen storage, yet the nature of their active sites remains poorly understood. This study investigates a nitrogen assembly carbocatalyst (NAC) for efficient and selective hydrocarbon dehydrogenation. For ethylbenzene, NAC maintains a selectivity of >99% towards styrene at a conversion of >20% for 120 hours at a weight hourly space velocity of...
Jie Zhang

The Long-Term Outcomes of Pulmonary Hypertension in Systemic Lupus Erythematosus (SLE-PAH) Vary Among Different Autoantibody-Based Clusters: An Observational, Longitudinal Study Conducted at a Single Centre in India

2 months 2 weeks ago
CONCLUSION: This study is the first to analyse SLE-PAH through cluster-based methods. Sm-RNP antibodies indicate more severe disease needing dual therapy, while multiple positive antibodies suggest a better prognosis, with most patients achieving PAH resolution.
Ritasman Baisya

Downregulation of SLC40A1 leads to iron accumulation in fibrotic lung fibroblasts

2 months 2 weeks ago
Iron is an essential nutrient for almost all organisms. However, excess iron generates reactive oxygen species and causes tissue injuries. Iron is implicated in idiopathic pulmonary fibrosis (IPF). In this study, we examined iron accumulation in fibrotic lung fibroblasts and the underlying mechanisms. We hypothesize that the downregulation of Solute Carrier Family 40 Member 1 (SLC40A1) results in iron accumulation in lung fibroblasts of IPF patients. Using a Prussian Blue iron staining, we found...
Quanjin Dang

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