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While individual therapy is a common treatment for depressive symptoms, adults with depressive symptoms also engage in couple and family therapy. To date, no studies have fully compared the effectiveness of these three therapy models in a naturalistic clinical setting. This study investigates the extent that the rates of changes in depressive symptoms across 16 sessions of treatment differ across individual, couple, and family therapy. We analyzed clinical data from the Marriage and Family...

CONCLUSIONS: This large-scale multiomic analysis revealed significant associations between SCLC subtypes and specific immune signatures and comutations. These findings provide insights into the molecular heterogeneity of SCLC, and highlight potential biomarkers for targeted therapies.

Facial abnormalities and brain defects in aborted equine fetuses are rarely reported, and the causes that predispose the occurrence of this condition are difficult to identify. This work reports the morphological and tomographic findings of a case of cryptophthalmia, microphthalmia, oronasal malformation, and hydrocephalus in an aborted equine fetus with umbilical cord torsion in the state of Mato Grosso, Brazil, from a primiparous Quarter Horse female, with 7 months of gestational age. The...

CONCLUSIONS: Medical student burnout varies significantly based on multiple factors, with concerning relationships between burnout, WH, and SHT. Medical schools should prioritize creating supportive learning environments and eliminating student mistreatment, with targeted interventions for vulnerable groups including female students, those with financial strain, and caregivers. Addressing these factors early in medical training may help mitigate burnout throughout physicians' careers, ultimately...