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the Gateway to Research in Oklahoma

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Gateway to Research in Oklahoma


Oklahoma Shared Clinical and Translational Resources U54 GM104938

Researchers

imgResearchers

The GRO: Researcher Portal provides resources, information, and training to help individuals or communities involved in performing clinical and translational research in Oklahoma.

Providers

imgProviders

The GRO: Provider Portal assists medical providers to identify clinical research opportunities in Oklahoma, tools for patient education, and evidence-based resources to improve patient care.

Patients

imgPatients

The GRO: Patient Portal can help patients and families to learn more about clinical and translational research and to connect with opportunities to participate in research opportunities in your communities.

Oklahoma Research Highlights

Mental health and adherence in CF: Self-efficacy and perceived barriers as mediators

3 months 2 weeks ago
CONCLUSIONS: This study found that when PWCF experienced mental health symptoms (either anxiety or depression), they were likely to report more interference from barriers to disease management or experience less medication self-efficacy, which was related to worse adherence. Building self-efficacy around taking medications may reduce the impact that mental health symptoms have on adherence. Care teams should also work with PWCF to minimize the impact of barriers on daily therapies.
Robin S Everhart

Short communication: Evaluation of mitochondrial surface area of selected metals and pesticides in RTL-W1 cells: A high-content imaging approach

3 months 2 weeks ago
In recent years, there has been increasing interest in utilizing fish cell culture in vitro assays, as alternatives to whole fish assays, for assessing the toxicity of aquatic pollutants. The fish cell line RTL-W1, derived from rainbow trout (Oncorhynchus mykiss) liver, was shown to retain several tissue specific features and to respond to chemical insults similarly to fish in vivo. In our study, we investigated the toxicity of two metals silver and cadmium and two pesticides azoxystrobin and...
Ozge Cemiloglu Ulker

Sodium-Glucose Cotransporter-2 Inhibitors and Arrhythmias: A Meta-Analysis of 38 Randomized Controlled Trials

3 months 2 weeks ago
CONCLUSIONS: SGLT2i therapy was associated with an overall lower risk of atrial arrythmia and SCD in patients with type 2 diabetes mellitus and/or HF or chronic kidney disease. However, SGLT2i therapy was not associated with a lower risk of ventricular arrhythmia.
Vikash Jaiswal

Platinum-free interval and response to platinum retreatment or lenvatinib/pembrolizumab in patients with recurrent endometrial cancer: A real-world endometrial cancer molecularly targeted therapy consortium cohort study

3 months 2 weeks ago
CONCLUSION: Longer PFI is associated with improved response to second-line treatment in patients with recurrent endometrial cancer. Despite utilization of PFI for real-world treatment decisions, it was not found to predict response between regimens at any given PFI.
Paulina J Haight

Developing and testing health warnings about alcohol and risk for breast cancer: Results from a national experiment with young adult women in the United States

3 months 2 weeks ago
CONCLUSION: Exposure to health warnings about alcohol consumption and breast cancer risk (vs. control) resulted in greater attention, fear, perceived message effectiveness, perceived severity of alcohol harms, and intentions to reduce alcohol consumption.
Zachary B Massey

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