CONCLUSION: Serum markers of endotoxin activity and inflammation are increased in adolescents with obesity but are not further increased in patients with mild to moderate MASLD.

Because ocean environments often lack clear barriers to dispersal, cryptobenthic reef fishes, with their limited mobility, are ideal for uncovering spatial patterns of evolutionary divergence. We conducted a comparative phylogeographic study of 23 of the 25 known species in the cryptobenthic genus Malacoctenus, integrating genome-wide single nucleotide polymorphisms (>500 individuals), geometric morphometrics and seascape data to evaluate historical and contemporary barriers in the Tropical...

Understanding the apparent temperature dependence of wetland methane emissions (E(M)) is critical for predicting climate-carbon feedbacks, yet current estimates remain constrained by observational limitations and methodological inconsistencies. The inherent biogeographic heterogeneity of wetland ecosystems combined with sparse, unevenly distributed flux measurements introduces substantial uncertainty in characterizing spatial patterns of E(M). This knowledge gap impedes accurate projections of...

Cellular functions arise from the coordinated action of proteoforms, which typically form multiproteoform complexes (MPCs), rather than functioning as isolated molecular entities. Deciphering the architecture and composition of MPCs is essential for linking proteoform diversity to biological function. Native top-down (nTD MS) and complex-down mass spectrometry (CxD MS) have emerged as powerful strategies to characterize MPCs, offering intact mass analysis as well as gas-phase sequencing either...

CONCLUSION: The MIS approach is utilized in a subgroup of patients with PAT with acceptable outcomes, shorter length of stay, and reduced costs. Further research is needed to develop strategies to increase the utilization of MIS in the management of patients with trauma.