Multisystem inflammatory syndrome in children (MIS-C) is a rare hyperinflammatory disorder that occurs in previously healthy pediatric patients after severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure or mild infection. MIS-C typically has mild kidney symptoms that resolve quickly. The kidney biopsy experience in pediatric coronavirus disease 2019 (COVID-19) and MIS-C is limited in the literature. Here, we describe a 17-year-old SARS-CoV-2 positive boy with features of MIS-C...

The effect of different sequences of invitations to Faecal Occult Blood Test (FOBT) screening regarding colorectal cancer (CRC) incidence has never been evaluated. In 2008-2012, all residents in Stockholm-Gotland, Sweden, born 1938-1954, were randomly assigned by birth year to different calendar years of invitation to guaiac-based FOBT (g) or Faecal Immunochemical Test (f) screening at 60-69 years (1-5 rounds), or not (0). Linkage was made to the national Cancer- and Cause of Death Registers on...

Cancer cachexia is a systemic metabolic syndrome driven by tumor-induced disruption of whole-body homeostasis. Characterized by skeletal muscle atrophy and adipose tissue loss, cachexia leads to functional decline, impaired quality of life, reduced treatment tolerance, and poor survival across multiple malignancies. Emerging evidence indicates that cachexia arises from complex and dynamic interactions between tumors and host organ systems, including immune, metabolic, endocrine, and neural...

Social exclusion is a common form of indirect aggression and carries significant social and health costs. Close friendships may protect against exclusion and shape physiological responses. While oxytocin and cortisol have received substantial attention in this context, progesterone is also implicated in affiliative motivation and may be sensitive to social threat. The present study examined progesterone responses to social exclusion and subsequent reunion with a close friend. Female participants...

Cancer is a global disease, yet a paradox persists: the most advanced research ecosystems are concentrated in countries with lower disease burden, whereas low- and middle-income countries (LMICs)-carrying 70% of the global cancer burden-face major constraints in research capacity. Closing this gap is essential for equitable progress in cancer prevention, diagnosis, and treatment. Researchers in LMIC are creatively adapting established technologies, research pipelines, and collaborative models...